Transferrin Receptor Antibody / TFRC / CD71

This antibody recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Mouse

The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Monoclonal

IgG1 κ

FACS, IF, WB

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the Transferrin receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Transferrin receptor antibody is available for research use only.