CD33 Antibody

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). [UniProt]

P20138

Rabbit

A portion of amino acids 88-117 from the human protein was used as the immunogen for this CD33 antibody.

Polyclonal

Ig

WB, ELISA

Antigen affinity purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the CD33 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This CD33 antibody is available for research use only.