TTR Antibody / Transthyretin / Prealbumin

Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

P02766

Mouse

Recombinant human full-length protein was used as the immunogen for the Transthyretin antibody.

Monoclonal

IgG1 κ

IHC-P, WB

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Transthyretin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Transthyretin antibody is available for research use only.