Anti-TGFalpha(TGFA/1119), CF568 conjugate

This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-beta (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

EGF-like TGF; ETGF; TFGA; TGF Type 1; TGFA; Wa1; Waved 1

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

TGFA

7039

170009

P01135

Secreted (extracellular)

Mouse

Human

Recombinant human full-length TGF alpha protein

TGF-Alpha

Monoclonal

IgG1 κ

TGFA/1119

CF568

Animal

IHC, FFPE (verified)

IHC,FFPE

Signal transduction

Jurkat or Ramos cells. Testicular Carcinoma

0.1 mg/mL

PBS, 0.1% BSA, 0.05% azide

6 kDa

Immunohistology formalin-paraffin 2-4 ug/mL|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Immunofluorescence 1-2 ug/mL|Optimal dilution for a specific application should be determined by user

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years