HRS Antibody / HGS / HGF-regulated tyrosine kinase substrate

Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

O14964

Mouse

Recombinant human HGS protein (amino acids R3-D777) was used as the immunogen for the HGF-regulated tyrosine kinase substrate antibody.

Monoclonal

IgG2a

WB, IHC-P, IF, FACS

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

After reconstitution, the HGF-regulated tyrosine kinase substrate antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This HGF-regulated tyrosine kinase substrate antibody is available for research use only.