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Anti-Hu TROP2 Alexa Fluor® 488

CAT:A4-898-T100Size:100 TestsPrice:Ask for quotation

Availability:

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Shipping:

This product ships without dry ice.

Background:

TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.

Specifications:

The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.

Certification:

RUO

Host:

Mouse

Species Reactivity:

Pig,Human

Negative Species:

Mouse

Immunogen:

TROP2-transfected CHO cells

Target Antigen:

TROP2

Isotype:

IgG2b κ

Clone:

TrMab-6

Applications:

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.

Validated Applications:

WB,ICC,FC,IHC

Format:

Alexa Fluor® 488

Buffer:

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations:

*Sayama Y, Kaneko MK, Kato Y: Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer. Mol Med Rep. 2021 Feb23(2):92., URL: https://pubmed.ncbi.nlm.nih.gov/33300065/,

Storage Conditions:

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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