CD59 Antibody

CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. [UniProt]

P13987

Mouse

Recombinant full-length human protein was used as the immunogen for the CD59 antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the CD59 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This CD59 antibody is available for research use only.