Quantitative sandwich ELISA for measuring Mouse BMP-binding endothelial regulator protein (BMPER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

• Additional information:BMPER contains a 39-amino acid signal peptide at the N terminus, 5 tandem cysteine-rich von Willebrand C (VWC)-like domains, 1 von Willebrand D domain, and a C-terminal trypsin inhibitor domain. Expression of recombinant Bmper showed the presence of full-length protein and a 42-kD C-terminal proteolytic fragment. In adult mice, expression of Bmper was high in heart, lung, and skin and low in brain. In situ hybridization of mouse tissue showed dynamic expression of Bmper during embryonic development. At embryonic day 9.5, Bmper staining was seen in the lamina reuniens adjacent to the telencephalic vesicle and in migrating branchial arch cells. At embryonic day 10.5, staining was seen in endothelial cells around the dorsal aorta and in adjacent migrating or mesenchymal cells.
• Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
• Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.