This Mouse Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) ELISA Kit employs a two-site sandwich ELISA to quantitate TNFAIP8.

• Additional information:TNFAIP8 was an early response gene, with expression peaking between 1.5 and 3 hours. TNF-alpha , a proapoptotic protein, also induced TNFAIP8 expression. The deduced 188-amino acid protein has a calculated molecular mass of 21 kD. TNFAIP8 contains a death effector domain (DED) that shares significant similarity with DED II of the FLIP family of cell death regulatory proteins. Northern blot analysis detected a 2.0-kb transcript in most adult and fetal human tissues, with high expression in adult spleen, lymph node, thymus, thyroid, bone marrow, and placenta, and in fetal liver, lung, and kidney. TNFAIP8 was also expressed in all cancer cell lines tested.The deduced protein contains 188 amino acids. In situ hybridization showed weak expression in adult human arteries.
• Storage and shipping:Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
• Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.