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ELISA kit for Rat Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B)

Supplier Abbkine · Catalog number: KTE100071-96T
Price

711 USD

Size
96T

Quantitative sandwich ELISA for measuring Rat Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:TNFRSF1B is a human gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1A. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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