This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

• Additional information:WB, FACS, IHC-P, IF
• Storage and shipping:Aliquot the RAR alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.