This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this mAb is completely blocked by the peptide used for raising this antibody. TGFa is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

• Additional information:FACS, IF, IHC-P
• Storage and shipping:Store the TGFa antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).