Bulk anti-Human CD2 In Vivo Antibody (LO-CD2a)

Seller Gentaur · Catalog number: ICH1193-50mg

Category product: Business and Industry > Scientific and Laboratory Research

 (0) Reviews

Price

2211.00 USD*

• Details

• Specifications: LO-CD2a strongly inhibits mixed lymphocyte culture (MLC) 3 and induces T cell apoptosis. Additionally, LO-CD2a does not induce proliferation of resting T cells, and inhibits T cell proliferation induced by OKT3 antibody, induces very low levels of cytokine release, and also inhibits cytokine production induced by OKT3, LO-CD2a strongly inhibits proliferation of peripheral blood mononuclear cells stimulated with soluble OKT3, and induces human T cell hyporesponsiveness. Adding LO-CD2a to a primary MLC inhibits the T cell proliferation response and has a subsequent inhibitory effect on the secondary immune response, thereby blocking primary and memory alloantigen proliferative responses. The human T cell hyporesponsiveness in the secondary MLC is restricted to alloantigens and occurs both in the absence of antibody and after cell surface re-expression of CD2
• Additional information: Low Endotoxin, anti-mouse, monoclonal antibody