Capmatinib 2HCl

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10mg

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Capmatinib 2HCl

Availability: Out of stock

Cat: MBS5750411-100mg

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Capmatinib 2HCl

Availability: Out of stock

Cat: MBS5750411-10mg

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Capmatinib 2HCl

Availability: Out of stock

Cat: MBS5750411-50mg

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Capmatinib 2HCl.H2O

Availability: Out of stock

Cat: MBS5764984-2mg

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Capmatinib 2HCl.H2O

Availability: Out of stock

Cat: T8825-1mg

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Specifications:
- Purity: 1
- CAS#: 1197376-85-4
- Molecular Weight: 485.34
- Bioactivity: INCB-28060(free base) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, INCB 28060 potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro.
Notes: For research use only.
Additional information:
- SMILES: Cl.Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
- Formula: C23H19Cl2FN6O

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