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HCV-371

HCV-371

Seller Gentaur · Catalog number: T32050-1g

Category product: Business and Industry > Scientific and Laboratory Research

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HCV-371
HCV-371

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HCV-371
HCV-371

Catalog number: T32050-1g / Size: 1g / Price: 0.01 USD (VAT free)

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  • Details
  • Specifications:
    • Purity: 0.98
    • CAS#: 675184-27-7
    • Molecular Weight: 312.37
    • Bioactivity: HCV-371 is a potent selective HCV NS5B polymerase inhibitor that shows broad inhibitory activity against NS5B RDRP and no inhibitory activity against a set of human polymerases (including mitochondrial DNA polymerase γ and other unrelated viral polymerases). This indicates that it is specific for HCV polymerase. Fluorescence binding studies have shown that HCV-371 binds to NS5b at an apparent dissociation constant of 150 nM, resulting in high selectivity and non-cytotoxicity in antiviral tests.
  • Notes: For research use only.
  • Additional information:
    • SMILES: N#CC1=CC=C(C)C2=C1C3=C([C@](OCC3)(CC(O)=O)CCC)N2
    • Formula: C18H20N2O3