K6-linkage Specific Polyubiquitin Rabbit pAb

Seller Gentaur · Catalog number: A18106

Category product: Business and Industry > Scientific and Laboratory Research

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Price

509.86 USD*

• Details

• Specifications: Other Modified Antibodies
• Storage and shipping: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
• Additional information: Polyubiquitin chains regulate diverse cellular processes through the ability of ubiquitin to form chains of eight different linkage types. Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair. it has been reported that modification at Lys-6 inhibits ubiquitin-dependent protein degradation, a failure of the ubiquitin-proteasome system could play a role in initiating the formation of degradation-resistant PHF tangles.