Mouse Transforming growth factor β2 (TGF-β2) ELISA Kit

Seller Gentaur · Catalog number: KTE70369-96T

Category product: Business and Industry > Scientific and Laboratory Research

 (0) Reviews

Price

1384.35 USD*

• Details

• Specifications:
  • Reactivity: Mouse
  • Sample types: serum, whole blood, plasma and other biological fluids
  • Detection range: Please inquire
  • Sensitivity: Please inquire Quantitative Sandwich ELISA
  • Method of detection: Colorimetric
• Storage and shipping: Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
• Notes: This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.
• Additional information: Tgfb2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Mice lacking a functional copy of this gene display developmental defects in multiple organs and perinatal lethality. Heterozygous mutant mice exhibit aortic root aneurysm. Tgfb2 encodes multiple isoforms that may undergo similar proteolytic processing.