Loading cart contents...
Pseudouridine / 5-ribosyluracil Rabbit pAb
Seller Gentaur · Catalog number: A18872
(0) Reviews
Availability:
Available
Price
476.12 USD*
Size
100μL
* Net price, excluding transport costs. Contact us to receive the current offer within 24 hours.
Ask for price
Availability: Out of stock
Cat: MBS9145453-5x005mL
Ask for more info: [email protected]
- Specifications: Other Modified Antibodies
- Storage and shipping: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
- Additional information: Pseudouridine is the most abundant post-transcriptional RNA modification, which presents mostly in non-coding RNAs such as tRNA, rRNA, snRNA and snoRNA.? Pseudouridine impacts various aspects of RNA biology, conferring distinct structural and functional properties to the RNA molecules that it decorates.? It is also reported that pseudouridine has been found in mRNA in both yeast and human by sequencing analysis.??? Replacing uridine to pseudouridine enhances structural stability of RNA, and is expected to affect rRNA processing, translation and pre-mRNA splicing. Also, aberrant pseudouridylation contributes to a variety of human diseases, including cancer and genetic disorders. Dysregulation of the pseudouridine epitranscriptome can arise from mutations and abnormal expression of pseudouridylation machinery, impacting protein translation and other cellular processes.