RecombinantENA-78/CXCL5(5-78aa),Human

Seller Gentaur · Catalog number: BK0029

Category product: Business and Industry > Scientific and Laboratory Research

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Price

3696.00 USD*

• Details

• Specifications: Epithelial cell­derived neutrophil­activating peptide (ENA­78) also known as C-X-C motif chemokine 5(CXCL5), is a small cytokine belonging to the CXC chemokine family. It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon, IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. Full length CXCL5 (78 aa) is trimmed at the N­terminal end by cathepsin G and chymotrypsin to ENA-74 (74 aa) and ENA-70 (70aa), with the shortened forms showing increased potency relative to full length CXCL5. CXCL5can signal through the CXCR2 receptor.Recombinant human ENA-78/CXCL5 (5-78a.a.) produced in E.coli is a single non-glycosylated polypeptide chain containing 74 amino acids. A fully biologically active molecule, rh ENA-78/CXCL5 (5-78a.a.) has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
• Storage and shipping: Lyophilized recombinant human ENA-78/CXCL5 (5-78a.a.) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human ENA-78/CXCL5 (5-78a.a.) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
• Additional information: Lyophilized after extensive dialysis against PBS.