TLE1 Recombinant Antibody

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.

Q04724

Rabbit

A recombinant human protein fragment (aa 175-338) was used as the immunogen for the Transducin-like enhancer protein 1 antibody.

Monoclonal

IgG κ

Recombinant

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the Transducin-like enhancer protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This TLE1 antibody is available for research use only.